Computational Techniques are being developed for the study of macromolecular complexes by SANS. Combined with selective Deuterium-labeling, they will make it possible to develop detailed structural models that will enable the understanding of function.

Another computation technique developed for the study of calculates solution small-angle X-ray and neutron scattering intensity profiles by ORNL-SAS. This makes it possible to develop from a wide variety of structures, including atomicresolution models of proteins and protein complexes, low-resolution models defined in any manner, or combinations of both.